One of the main causes of infertility of women is an excessive level of the female sexual hormones estrogens. The level of gonadotropic hormones may be reduced due to the hyperfunction of the estrogenic receptors, so that ovulation disappears. In order to restore ovulation, doctors prescribe Clomid.
Clomid is a synthetic biological analogue of estrogens which is used for the recovery of the hormone balance in the female body. This medicine contains an active ingredient Clomiphene which has antiestrogen characteristics. When Clomid (synthetic estrogens) goes to the body, the brain center gets a signal that these hormones are enough, and the brain sends a signal blocking their action to the estrogenic receptors.
Using Clomid blocks estrogen receptors in the basal gland and ovaries, so that the level of gonadotropic hormones is restored. In case of the increased level of gonadotropic hormones, the reproductive function of women is restored, ovulation appears, and a chance to become pregnant is increased.
Clomid is not able to lower the estrogen level in the blood but it is able to block estrogenic receptors in order to restore a balance of hormones in the body of women and men. In urology, Clomid is used during the high reduction of the endogenic testosterone level. This medicine quickly restored the level of FSH and LH due to which the level of the endogenic testosterone is increased.
Indications for the use
- Lack of ovulation
- The lack of endogenous testosterone in males after hormonal pharmacological courses
- Secondary hypovarianism
In what dose is Clomid used?
To restore ovulation in women, Clomid is taken with in short term – 5 days. The treatment begins from the 5th day of the menstrual cycle (if menstruation is absent, the treatment can be started at any day). The daily dose of Clomid is 50 mg on the first stage of the treatment.
A general therapeutic dose is 250 mg of Clomid within entire cycle of the treatment. After the end of the first cycle of the treatment, a woman should have ovulation. If it did not happen, the treatment should be repeated in a month.
The daily dose of Clomid is increased up to 150 mg within the second course of the treatment. Clomid 150 mg is taken according to the standard scheme within 5 days, and then ovulation should be expected. Men are recommended to take Clomid 50 mg 1-2 times per day, within 6-7 weeks to restore a normal function of testicles.
In case of the overdose with Clomid the following side effects appear: allergic skin reactions, flushing, blurred vision, abdominal pain, uterine bleeding of unknown origin, pain in the breast. In case of the overdose, a symptomatic treatment is conducted, and the use of Clomid is stopped.
A significant medical interaction of Clomid with other medical products have not been detected. But if you decided to begin the use of Clomid, inform your doctor or pharmacist about drugs you are taking at the moment.
- Patients using Clomid are recommended to check liver. The use of Clomid is contraindicated during severe pathologies of liver
- If a woman was diagnosed ovarian cyst or malignant tumor of genitals during pelvic examination, the use of Clomid is ceased.