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Lisinopril

Generic Name: Lisinopril

Brand Names: Zestril, Prinivil, Qbrelis

Dosage Package: 10mg, 50mg, 2.5mg

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What is Lisinopril?

Lisinopril is a medical product which maintains healthy functions of the cardiovascular system and reduces high blood pressure.

Lisinopril provides a vasodilating, cardioprotective, hypotensive action, decreases a general peripheral resistance of the blood vessels, reduces hypertrophy of myocardium, provides positive influence on the blood supply of the affected myocardium.

Patients with chronic heart failure use the drug to increase a length and quality of life, reduce the symptoms of the disease and prevent a disease development.

The drug does not influence on the concentration of glucose in the blood in patients with pancreatic diabetes and does not lead to the cases of the hypoglycemia. Moreover, it does not cause hypotension because it has a soft action and is meant to control the functions of the cardiovascular system and not for urgent arresting of the attacks. So, the use of Lisinopril is pointless during hypertonic crisis. A hypotensive effect occurs in 6-8 hours after the use of the pill, and the maximal effect occurs within 12-24 hours.

Who should take Lisinopril?

Lisinopril is prescribed patients with chronic arterial hypertension who need a long-term quality therapy. Moreover, the drug is effectively used in the treatment of chronic heart failure, and diabetic nephropathy.

The use of Lisinopril within 24 hours after myocardial infarction helps to quickly restore and improve the function of left ventricle.

How to take Lisinopril?

A scheme of the use of Lisinopril will depend on the purposes of the use of the drug. At first, it is necessary to have a medical examination, estimate the blood pressure and consult a cardiologist. You may be prescribed an individual therapy after the medical examination and a dose regimen. If not, Lisinopril should be used in the standard dose:

  • Arterial hypertension – 20-40 mg per day
  • Heart failure – 2,5-5 mg (at the beginning of the treatment) up to 20 mg per day during a long-term treatment
  • Acute myocardial infarction in the first 24 hours – 5 mg, then 5 mg in 24 hours, then 10 mg in two days, and then 10 mg once per day within 4-6 weeks

Aged patients have more intensive prolonged hypotensive action due to the reduced speed of the excretion of Lisinopril. Therefore senior patients should start the treatment from the minimal dose of 2,5-5 mg per day depending on the intensity of the hypotensive effect (gradually increasing the dose).

What are side effects?

The most common side effects are dizziness, headache, weakness, diarrhea, dry cough, nausea, chest tightness or tachycardia. These symptoms usually appear in 3-4% of patients. But they are light, and therefore you may not even feel any negative symptoms.

Special recommendations

  • If you have any severe diseases such as disorder of cerebral circulation, autoimmune diseases, oppression of bone marrow hematopoiesis, stenosis of the renal arteries, ischemic heart disease, an additional medical examination is needed. The use of Lisinopril may be contraindicated
  • The use of Lisinopril is contraindicated during pregnancy. If pregnancy happened during the therapy, the use of the drug should be cancelled as soon as possible.

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