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nexium

Nexium

Generic Name: Esomeprazole

Brand Names: Nexium, Axiago, Esomac, Esomeprazole Strontium, Esopral

Dosage Package: 40 mg, 20 mg

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Acute pain in stomach and heartburning are the first sign of the gastric ulcer. An attack of the ulcer can be accompanied by bleedings and other unpleasant symptoms, and therefore patients need an urgent and effective help. One of the best drugs is Nexium to arrest the symptoms of the gastric ulcer.

General description

Nexium is a proton pump inhibitor and contains an active ingredient Esomeprazole. This is the most promising medicine for the treatment of the ulcers of stomach and duodenum because it is able to lower the production of the hydrochloric acid in a short time.

One of the main causes of the appearance of ulcers on the mucous membrane of the gastro-intestinal tract is a high acidity of the gastric juice. Nexium lowers the production of the hydrochloric acid, so that an acidity of the gastric juice is reduced, and the stomach walls are not eaten.

Nexium slightly enhances a production of the protective mucus which coats the mucous membrane of the gastro-intestinal tract and helps to accelerate the healing of ulcers and erosions.

A concentration of the hydrochloric acid is reduced by 90% during the everyday use of Nexium for the acute condition of the gastric ulcer. This medicine is effective in the treatment of the ulcer symptoms, as well as prevention of the erosive-ulcerous affections of the gastro-intestinal tract.

Indications for the use

  • Gastroesophageal reflux disease
  • Stomach ulcer
  • Duodenal ulcer
  • Prevention of gastric ulcers while taking non-steroidal anti-inflammatory drugs and strong analgesics
  • Zollinger-Ellison syndrome
  • Combination therapy of gastric ulcers associated with Helicobacter pylori

In what dose is Nexium used?

The Nexium tablets are taken once per day regardless of the meals. The tablets should be taken with a full glass of water for better dissolution.

  • If gastroesophageal reflux disease and gastric ulcer caused by the high acidity of the gastric juice, patients are prescribed a tablet of Nexium 40 mg per day within a month
  • To treat the gastric ulcer associated with Helicobacter pylori, Nexium is used in the dose of 40 mg in combination with amoxicillin or other penicillin antibiotics within 7-14 days
  • If the gastric ulcer caused by the use of NSAIDs, Nexium is taken in the dose of 40 mg within 6-8 weeks

Overdose

At the moment, rare cases of the overdose with Nexium are recorded. The overdose symptoms are general weakness, vomiting, dyspepsia, and headache.

If the overdose symptoms appear, it is necessary to have a stomach lavage and consult a physician.

Medical interaction

  • As other proton pump inhibitors, Nexium should not be used with atazanavir and nelfinavir
  • A reduction of the gastric juice due to the treatment with Esomeprazole can lead to the change of the absorption of drugs that depend on the acidity
  • It has been proved that Nexium interacts with some antiretroviral drugs, and therefore if you are taking medicines from this group, consult a physician

Preventive measures

  • Nexium is contraindicated for the use during the allergic reaction to the active ingredient Esomeprazole and during hereditary fructose intolerance
  • Children under 12 years old are not prescribed Nexium because there is no information about the efficiency and safety of the drug in this group of patients
  • The use of Nexium is possible during pregnancy but in seldom cases, and under doctor’s supervision.

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